Project Leaders

Project leaders RTG 1715

CRA1  Metabolic Stress

Subproject Name
SP2 The impact of metabolic stress on inflammasome activation in endothelial cells

Regine Heller
SP16 GR acetylation Thorsten Heinzel
SP10 Alpha-Tocopherol Metabolites Andreas Koeberle / Stefan Lorkowski
SP28 Regulation of rDNA silencing via PAPAS Holger Bierhoff
SP29 Epigenetic stress response during calorie restriction in ageing intestine Francesco Neri


CRA2  Neuronal Stress

Subproject Name
SP5 Signalling pathways controlling actin dynamics in adaptive stress responses in the brain underlying neuronal plasticity

Britta Qualmann
SP6 Role of Arl6iP1 in adaptive neuronal stress response Christian Hübner
SP7 Peripheral Nerve Aging: Maintenance, Repair, and CCL11 as a potential ageing factor Helen Morrison
SP18 The actin nucleator Cobl as target in excitotoxicity induced by ischemic stroke Britta Qualmann / Christiane Frahm
SP19 Organizational and signaling cues in membranes Michael Kessels


CRA3  Inflammatory Stress

Subproject Name
SP8 Tolerance or sensitisation: Molecular signatures of enduring microglial adaptation

Reinhard Bauer
SP9 Mechanisms of Disease tolerance in Sepsis-associated liver failure: Preventing progression of infection to sepsis with organ failure Michael Bauer / Ignacio Rubio
SP11 Stress signatures controlling gastrointestinal contractions Stefan H. Heinemann
SP22 Promoting tissue tolerance by targeting the interplay of autophagy and the inflammasome in septic liver failure Tony Bruns / Sachin Deshmuk
SP30 Mitochondrial Dynamics in Innate Immune Training Sebastian Weis


CRA4  Genotoxic Stress

Subproject Name
SP13 Molecular mechanisms linking adaptive DNA damage responses to immune cell activation and inflammation

Christian Kosan
SP14 The dissection of PARP1 functions Zhao-Qi Wang
SP23 The role of sphingosine 1-phosphate (S1P) signalling in genotoxic stress-induced protection from septic shock Markus Gräler
SP26 Dissecting genetic basis of radiation hormesis and testing effects of low dose ionising radiation on homeostasis of murine tissues Maria Ermolaeva
SP31 Targeting metabolic pathways involved in mutator hormesis in human cancer cells​ Helmut Pospiech / Berit Jungnickel

Michael Bauer

SP9 | University Hospital Jena
Michael Bauer, Prof. Dr
Coordinator / Project leader
Michael Bauer
Image: Michael Szabo / UKJ
Clinic for Anaesthesiology and Intensive Care Medicine
Am Klinikum 1
07747 Jena Google Maps site planExternal link

Reinard Bauer

SP8 | University Hospital Jena
Reinhard Bauer, apl. Prof. Dr
Project leader
Reinhard Bauer
Image: Michael Szabo, UKJ
CMB, Institute for Molecular Cell Biology
Hans-Knöll-Str. 2
07745 Jena Google Maps site planExternal link

Holger Bierhoff

SP 28 | FSU Jena
Holger Bierhoff, Dr
Project leader
Holger Bierhoff
Image: Evelyn Kästner
CMB, Room 132
Hans-Knöll-Straße 2
07745 Jena Google Maps site planExternal link

Tony Bruns

SP22 | University Hospital Jena
Tony Bruns, Univ.-Prof. Dr
Project leader
Tony Bruns
Image: Bruns
Universitätsklinikum Aachen
Pauwelsstraße 30
52074 Aachen Google Maps site planExternal link

Maria Ermolaeva

SP26 | FLI Jena
Maria Ermolaeva, Dr
Project leader
Maria Ermolaeva
Image: Augenwerke-Fotografie
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)
Beutenbergstr. 11
07745 Jena Google Maps site planExternal link

Christiane Frahm

SP18 | University Hospital Jena
Christiane Frahm, Dr
Project leader
Christiane Frahm
Image: fotostudio arlene knipper
Hans Berger Department of Neurology
Am Klinikum 1
07747 Jena Google Maps site planExternal link

Markus Gräler

SP23 | University Hospital Jena
Markus Gräler, Prof. Dr
Project leader
Markus Gräler
Image: Poldi
AG Biochemistry of Sepsis (BiochSep)
Hans-Knöll-Str. 2
07745 Jena Google Maps site planExternal link

Thorsten Heinzel

SP16 | FSU Jena
Thorsten Heinzel, Univ.-Prof. Dr
Speaker of RTG 1715 / Project leader
Thorsten Heinzel
Image: Anne Günther (University of Jena)

Regine Heller

SP2 | University Hospital Jena
Regine Heller, apl. Prof. Dr
Project leader
Heller, Regine
Image: Michael Szabo, UKJ
CMB, Institute for Molecular Cell Biology
Hans-Knöll-Str. 2
07745 Jena Google Maps site planExternal link

Christian Hübner

SP6 | University Hospital Jena
Christian Hübner, Prof. Dr
Project leader
Christian Hübner
Image: Hübner / UKJ
Institute of Human Genetics
Am Klinikum 1
07747 Jena Google Maps site planExternal link

Berit Jungnickel

SP31 | FSU Jena
Berit Jungnickel, Prof. Dr
Project leader
Bioinstrumentezentrum
Winzerlaer Straße 2
07745 Jena Google Maps site planExternal link

Michael Kessels

SP19 | University Hospital Jena
Michael Kessels, PD Dr
Project leader
Michael Kessels
Image: Kessels, UKJ
Institute for Biochemistry I
Nonnenplan 2
07743 Jena Google Maps site planExternal link

Andreas Koeberle

SP25 | FSU Jena
Andreas Koeberle, Prof. Dr
Project leader
Andreas Koeberle
Image: Koeberle
Michael Popp Forschungsinstitut
Mitterweg 24
A-6020 Innsbruck / Austria Google Maps site planExternal link

Christian Kosan

SP13 | FSU Jena
Christian Kosan, PD Dr
Project leader
Christian Kosan
Image: Anne Günther (University of Jena)
CMB, Room 133
Hans-Knöll-Straße 2
07745 Jena Google Maps site planExternal link

Helen Morrison

SP7 | FLI Jena
Helen Morrison, apl. Prof. Dr
Prohject leader
Helen Morrison
Image: FLI
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)
Beutenbergstr. 11
07745 Jena Google Maps site planExternal link

Francesco Neri

SP29 | FLI Jena
Francesco Neri, Dr
Project leader
Francesco Neri
Image: Francesco Neri / FLI
Leibniz Institute on Aging – Fritz Lipmann Institute (FLI)
Beutenbergstr. 11
07745 Jena Google Maps site planExternal link

Helmut Pospiech

SP31 | FSU Jena
Helmut Pospiech, Dr
Project leader
Helmut Pospiech
Image: Pospiech, FLI
Leibniz Institute on Aging – Fritz Lipmann Institute (FLI)
Beutenbergstraße 11
07745 Jena Google Maps site planExternal link

Britta Qualmann

SP5 | University Hospital Jena
Britta Qualmann, Univ.-Prof. Dr
Coordinator / Project leader
Britta Qualmann
Image: UKJ
Institute for Biochemistry I
Nonnenplan 2
07743 Jena Google Maps site planExternal link

Ignacio Rubio

SP9 | University Hospital Jena
Ignacio Rubio, apl. Prof. Dr
Project leader
Ignacio Rubio
Image: Rubio, UKJ
Dept. for Anesthesiology and Intensive Care
Am Klinikum 1
07747 Jena Google Maps site planExternal link

Zhao-Qi Wang

SP14 | FLI Jena
Zhao-Qi Wang, Prof. Dr
Coordinator / Project leader
ZQ Wang
Image: FLI Jena
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)
Beutenbergstr. 11
07745 Jena Google Maps site planExternal link

Sebastian Weis

SP30 | Jena University Hospital
Sebastian Weis, Dr
Project leader
Sebastian Weis
Image: UKJ
Dept. for Anesthesiology and Intensive Care
Am Klinikum 1
07747 Jena Google Maps site planExternal link