Publications

Ziegler AC, Müller T, Gräler MH. (2021) Sphingosine 1-phosphate in sepsis and beyond: Its role in disease tolerance and host defense and the impact of carrier molecules.External link
Cell Signal. 2021 Feb;78:109849. doi: 10.1016/j.cellsig.2020.109849 → CRA4

Laiqi T, Marx C, Hudalla H, Haas F, Große S, Wang Z, Heller R, Bauer M, Wetzker R, Bauer R. (2021) The Role of Pathogen Dose and PI3Kγ in Immunometabolic Reprogramming of Microglia for Innate Immune MemoryExternal link. Int J of Mol Sci 2021, 22(5), 2578 → CRA1 / CRA3

Ziegler AC, Gräler MH. (2021) Barrier maintenance by S1P during inflammation and sepsis.External link Tissue Barriers. 2021 Jun 21:1940069. doi: 10.1080/21688370.2021.1940069. Epub ahead of print. PMID: 34152926. → CRA4

Jentho E, Novakovic B, Ruiz-Moreno C, Kourtzelis I, Martins R, Chavakis T, Soares MP, Kalafati L, Guerra J, Roestel F, Bohm P, Godmann M, Grinenko T, Eugster A, Beretta M, Joosten LAB, Netea MG, Stunnenberg HG, Bauer M, Weis S. (2021) Heme Induces Innate Immune MemoryExternal link. 2019 Dec; BioRxiv; doi: https://doi.org/10.1101/2019.12.12.874578 (in press- PNAS) → CRA3

Mourits VP, van Puffelen JH, Novakovic B, Bruno M, Ferreira AV, Arts RJ, Groh L, Crișan TO, Zwaag J, Jentho E, Kox M, Pickkers P, van de Veerdonk FL, Weis S, Oosterwijk E, Vermeulen SH, Netea MG, Joosten LA. (2021) Lysine methyltransferase G9a is an important modulator of trained immunityExternal link. Clin Transl Immunology. 2021;10(2):e1253. → CRA3

Stengel S, Steube A, Köse-Vogel N, Kirchberger-Tolstik T, Deshmukh S, Bruns T. (2021) Primed circulating monocytes are a source of IL-1β in patients with cirrhosis and ascitesExternal link. Gut. 2021 Mar;70(3):622-623. → CRA4

Schmidt C, Schneble-Löhnert N, Lajqi T,  Wetzker R, Müller JP, Bauer R. (2021) PI3Kgamma mediates microglial proliferation and cell viability via ROSExternal link.
Cells 2021, 10, 2534. https://doi.org/10.3390/cells10102534 → CRA3

Marx C, Sonnemann J, Beyer M, Maddocks ODK, Lilla S, Hauzenberger I, Piée-Staffa A, Siniuk K, Nunna S, Marx-Blümel L, Westermann M, Wagner T, Meyer FB, Thierbach R, Mullins CS, Kdimati S, Linnebacher M, Neri F, Heinzel T, Wang ZQ, Krämer OH. (2021) Mechanistic insights into p53-regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cellsExternal link. Mol Oncol. 2021 Jul 14. doi: 10.1002/1878-0261.13060. Online ahead of print. → CRA1 / CRA4

Gutiérrez-Gutiérrez O, Felix DA, Salvetti A, Amro EM, Hems A, Pietsch S, Koeberle A, Rudolph KL, González-Estévez C (2021) Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein responseExternal link. EMBO rep 2021 Aug 4;22(8):e52905.doi: 10.15252/embr.202152905 → CRA1

Lu J, Krepelova A, Rasa SMM, Annunziata F, Husak O, Adam L, Nunna S, Neri F. (2021) Characterization of an in vitro 3D intestinal organoid model by using massive RNAseq-based transcriptome profilingExternal link Sci Rep. 2021 Aug 17;11(1):16668. doi: 10.1038/s41598-021-96321-8. → CRA1

Di Sanzo S, Spengler K, Leheis A, Kirkpatrick JM, Rändler TL, Baldensperger T, Dau T, Henning C, Parca L, Marx C, Wang ZQ, Glomb MA, Ori A, Heller R. (2021) Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferationExternal link. Nat Commun. 2021 Nov 18;12(1):6743. doi: 10.1038/s41467-021-26982-6. PMID: 34795246. → CRA1 / CRA4

Ji Y, Koch D, González Delgado J, Günther M, Witte OW, Kessels MM, Frahm C, Qualmann B. (2021) Post-stroke dendritic arbor regrowth requires the actin nucleator Cobl. PLOS biol. DOI: 10.1371/journal.pbio.3001399 (epub ahead) → CRA2

Spengler K, Kryeziu N, Große S, Mosig AS, Heller R.( 2020) VEGF Triggers Transient Induction of Autophagy in Endothelial Cells via AMPKα1.  External linkCells. Mar 11 2020;9(3):687. doi: 10.3390/cells9030687. PMID: 32168879; PMCID: PMC7140637. → CRA1

Jeya Paul J, Weigel C, Müller T, Heller R, Spiegel S, Gräler MH. (2020)
Inflammatory Conditions Disrupt Constitutive Endothelial Cell Barrier Stabilization by Alleviating Autonomous Secretion of Sphingosine 1-Phosphate. External linkCells. 2020 Apr 10;9(4):928. doi: 10.3390/cells9040928. PMID: 32290092; PMCID: PMC7226983. → CRA1 / CRA4

Sharifi S, da Costa HFR, Bierhoff H. (2020) The circuitry between ribosome biogenesis and translation in stem cell function and ageingExternal link.
Mech Ageing Dev. 2020 Jul;189:111282. → CRA1

Weigel C, Hüttner S, Ludwig K, Krieg N, Hofmann S†, Schröder NH, Robbe L, Kluge S, Nierhaus A, Winkler MS, Rubio I, von Maltzahn J , Spiegel S, Gräler MH. (2020) S1P lyase inhibition protects against sepsis by promoting disease tolerance via the S1P/S1PR3 axis.External link
EBioMedicine  Volume 58, August 2020, 102898. → CRA4

Ludwig K, Husain RA, Rubio I. (2020) mTORC1 Is Not Principally Involved in the Induction of Human Endotoxin ToleranceExternal link.
Front Immunol. 2020 Aug 7;11:1515. → CRA4

Lajqi T, Stojiljkovic MR, Williams DL, Hudalla H, Bauer M, Witte OW, Wetzker R, Bauer R, Schmeer C. (2020) Memory-Like Responses of Brain Microglia Are Controlled by Developmental State and Pathogen Dose.External link
Front. Immunol., 25 September 2020 → CRA3

Lang GP, Ndongson-Dongmo B, Lajqi T, Brodhun M, Han Y, Wetzker R, Frasch MG, Bauer R. (2020) Impact of ambient temperature on inflammation-induced encephalopathy in endotoxemic mice-role of phosphoinositide 3-kinase gamma.External link
J Neuroinflammation. 2020 Oct 7;17(1):292. doi: 10.1186/s12974-020-01954-7. → CRA3

Thuy AV, Jeya Paul J, Weigel C, Ziegler AC, Guntinas-Lichius O, Gräler MH. (2020) Validation of a monoclonal antibody directed against the human sphingosine 1-phosphate receptor type 1External link.
J Immunol Methods. 2020 Dec 30:112953. doi: 10.1016/j.jim.2020.112953. → CRA4

Coburger I, Yang K, Bernert A, Wiesel E, Swain SM, Sahoo N, Schönherr R, Hoshi T, Heinemann SH. (2020) Impact of intracellular hemin on N-type inactivation of voltage-gated KExternal link⁺ channelsExternal link.
Pflugers Arch – European Journal of Physiology 472 551–560 PMID: 32388729. DOI: 10.1007/s00424-020-02386-1 → CRA3

Espada L, Dakhovnik A, Chaudhari P, Martirosyan A, Miek L, Poliezhaieva T, Schaub Y, Nair A, Döring N, Rahnis N, Werz O, Koeberle A, Kirkpatrick J, Ori A, Ermolaeva MA. (2020) Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegans.External link
Nat Metab. 2020 Nov;2(11):1316-1331 → CRA4

Wirtz TH, Reuken PA, Jansen C, Fischer P, Bergmann I, Backhaus C, Emonzpohl C, Reißling J, Brandt EF, Koenen MT, Schneider KM, Schierwagen R, Brol MJ, Chang J, Zimmermann HW, Köse-Vogel N, Eggermann T, Kurth I, Stoppe C, Bucala R, Bernhagen J, Praktiknjo M, Stallmach A, Trautwein C, Trebicka J, Bruns T, Berres ML. (2020) Balance between macrophage migration inhibitory factor and sCD74 predicts outcome in patients with acute decompensation of cirrhosisExternal link. JHEP Rep, 2020 Dec 17;3(2):100221 → CRA4

Stengel S, Quickert S, Lutz P, Ibidapo-Obe O, Steube A, Köse-Vogel N, Yarbakht M, Reuken PA, Busch M, Brandt A, Bergheim I, Deshmukh SD, Stallmach A, Bruns T.  (2020) Peritoneal Level of CD206 Associates with Mortality and an Inflammatory Macrophage Phenotype in Patients with Decompansated Cirrhosis and Spontaneous Bacterial PeritonitisExternal link. Gastroenterology 2020 May;158(6):1745-1761. → CRA4

Ibidapo-Obe O, Stengel S, Köse-Vogel N, Quickert S, Reuken PA, Busch M, Bauer M, Stallmach A, Bruns T. (2020) Mucosal-Associated Invariant T Cells Redistribute to the Peritoneal Cavity During Spontaneous Bacterial Peritonitis and Contribute to Peritoneal InflammationExternal link. Cell Mol Gastroenterol Hepatol. 2020;9(4):661-677. → CRA4

Espada L#, Dakhovnik A#, Chaudhari P#, Martirosyan A, Miek L, Poliezhaieva T, Schaub Y, Nair A, Döring N, Rahnis N, Werz O, Koeberle A, Kirkpatrick J, Ori A, Ermolaeva MA (2020) Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegansExternal link. Nat Metab. 2020 Nov;2(11):1316-1331,
#- first co-authorship → CRA3 / CRA4

Stojiljkovic MR, Ain Q, Bondeva T, Heller R, Schmeer C, Witte OW. (2019) Phenotypic and functional differences between senescent and aged murine microglia.External link
Neurobiol Aging. 2019 Feb;74:56-69. → CRA1 / CRA3

Ndongson-Dongmo B, Lang GP, Mece O, Hechaichi N, Lajqi T, Hoyer D, Brodhun M, Heller R, Wetzker R, Franz M, Levy FO, Bauer R. (2019) Reduced ambient temperature exacerbates SIRS-induced cardiac autonomic dysregulation and myocardial dysfunction in mice.External link
Basic Res Cardiol. 2019 Apr 23;114(3):26. → CRA1 / CRA3

Bocker HT, Heinrich T, Liebmann L, Hennings JC, Seemann E, Gerth M, Jakovčevski I, Preobraschenski J, Kessels MM, Westermann M, Isbrandt D, Jahn R, Qualmann B, Hübner CA. (2019) The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA ReleaseExternal link. Cereb Cortex Sep 13;29(10):4263-4276. → CRA2

Wolf D, Hofbrucker-MacKenzie SA, Izadi M, Seemann E, Steiniger F, Schwintzer L, Koch D, Kessels MM^§, Qualmann B^§. (2019) Ankyrin repeat-containing N-Ank proteins shape cellular membranesExternal link. Nat Cell Biol. 2019 Oct;21(10):1191-1205. → CRA2
^§ shared corresponding authorship

Kamaletdinova K, Fanaei-Kahrani Z, Wang  ZQ. (2019) The Enigmatic Function of PARP1: From PARylation Activity to PAR ReadersExternal link. Cells Dec 12;8(12):1625. → CRA4

Yang, K, Coburger I, Langner J, Peter N, Hoshi T, Schönherr R, Heinemann SH. (2019) Modulation of KExternal link⁺ channel N-type inactivation by sulfhydration through hydrogen sulfide and polysulfidesExternal link.
Pflugers Arch – European Journal of Physiology 471 557–571. PMID: 30415410 → CRA3

Laiqi T, Lang GP, Haas F, Williams LD, Hudalla H, Bauer M, Groth M, Wetzker R, Bauer R. (2019) Memory-Like Inflammatory Responses of Microglia to Rising Doses of LPS: Key Role of PI3KγExternal link.
Front Immunol. 2019, 10: 2492 → CRA3

Lajqi T, Stojiljkovic M, Wetzker R (2019). Toxin-induced hormesis may restrain agingExternal link." Biogerontology 20(4): 571-581.*All authors equally contributed to the manuscript → CRA3

Weis S, Heindl M, Carvalho T, Jentho E, Lorenz J, Sommerer I, et al. (2019) Azithromycin does not improve disease severity in acute experimental pancreatitisExternal link. PLoS One. 2019;14(5):e0216614. → CRA3

Köse-Vogel N, Stengel S, Gardey E, Kirchberger-Tolstik T, Reuken PA, Stallmach A, Bruns T. (2019) Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines. Cells 2019 Dec 28;9(1):79 → CRA4

Yarbakht M, Pradhan P, Köse-Vogel N, Bae H, Stengel S, Meyer T, Schmitt M, Stallmach A, Popp J, Bocklitz TW, Bruns T. (2019) Non-linear multimodal imaging characteristics of early septic liver injury in a mouse model of peritonitis. External linkAnal. Chem. 2019 Sep 3;91(17):11116-11121. → CRA4

Bocker HT, Heinrich T, Liebmann L, Hennings JC, Seemann E, Gerth M, Jakovčevski I, Preobraschenski J, Kessels MM, Westermann M, Isbrandt D, Jahn R, Qualmann B, Hübner CA (2019) The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA ReleaseExternal link. Cereb Cortex, 2019 Sep 13;29(10):4263-4276. → CRA2

Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Harold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita Y, Rudolph KL (2019) Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammationExternal link. J Exp Med 2019, 216(1), 152-75 → CRA1

Glatzel DK, Koeberle A, Pein H, Loeser K, Stark A, Keksel N, Werz O, Müller R, Bischoff I, Fürst R (2018) Acetyl-CoA carboxylase 1 regulates endothelial cell migration by shifting the phospholipid composition External linkJ Lipid Res 59: 298-311→ CRA1 / CRA3

Izadi M, Schlobinski D, Lahr M, Schwintzer L, Qualmann B^§, Kessels MM^§. (2018) Cobl-like promotes actin filament formation and dendritic branching using only a single WH2 domain.External link
J Cell Biol. 2018 Jan 2;217(1):211-230. → CRA2
^§shared corresponding authorship

Hou W, Nemitz S, Schopper S, Nielsen ML, Kessels MM^§, Qualmann B^§. Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator CoblExternal link. Dev Cell. 2018 Apr 23;45(2):262-275.e8. → CRA2
^§shared corresponding authorship

Marx C, Marx-Blümel L, Thierbach R, Poburski D, Becker S, Wittig S, Lehmann R, Slevogt H, Heinzel T, Wang ZQ, Beck JF, Sonnemann J (2018) The sirtuin 1/2 inhibitor tenovin-1 induces a nonlinear apoptosis-inducing factor-dependent cell death in a p53 null Ewing's sarcoma cell lineExternal link. Investigational New Drugs, Jun;36(3):396-406. → CRA1 / CRA4

Balakrishnan P, Liebe T, Amro E, Dhaka L, Heinzel T, Heller R (2018) Metabolic stress - signaling and metabolic adaptation.
In: The Science of Hormesis in Health and Longevity, (S. I. S. Rattan, M. Kyriazi, Ed.) Academic Press 139-148 → CRA1

Mägdefrau AS, Ludwig K, Weigel C, Köse N, Guerra GM, Dakhovnik A, Kosan C (2018)
DNA-Damage-Induced Hormetic Responses.
In: The Science of Hormesis in Health and Longevity, (S. I. S. Rattan, M. Kyriazi, Ed.) Academic Press 149-159 → CRA4

Jentho E, Lajqi T, Yang K, Winkler R, Stojiljkovic M, Wetzker R, Bauer M (2018)
Pathogen-induced hormetic responses
in: The Science of Hormesis in Health and Longevity (S. I. S. Rattan, M. Kyriazi, Ed.) Academic Press 161-170 → CRA3

Hofbrucker-MacKenzie SA, Sivaprakasam I, Ji Y, Kessels MM, Qualmann B (2018)
Neuronal Stress and Its Hormetic Aspects.
in: The Science of Hormesis in Health and Longevity (S. I. S. Rattan, M. Kyriazi, Ed.) Academic Press 171-180 → CRA2

Spengler K, Große S, Kryeziu N, Knierim A, Heller R. (2018) Studying the Role of AMPK in Angiogenesis. External linkMethods Mol Biol. 2018;1732:519-537. → CRA1

Izadi M, Hou W, Qualmann B, Kessels MM. (2018) Direct effects of CaExternal link²⁺/calmodulin on actin filament formationExternal link. Biochem Biophys Res Commun. 2018 Nov 25;506(2):355-360. doi: 10.1016/j.bbrc.2018.07.159. → CRA2

Reinhold AK, Jentho E, Schäfer ST, Bauer M, Rittner H. (2018) Epigenetics: Important aspects for anesthesiologists, pain and intensive care physicians.External link Anaesthesist. 2018 Apr;67(4):246- 254. Review. German. → CRA3

Heinze I, Bens M, Calzia E, Holtze S, Dakhovnik O, Sahm A, Kirkpatrick JM, Szafranski K, Romanov N, Sama SN, Holzer K, Singer S, Ermolaeva M, Platzer M, Hildebrandt T, Ori A (2018) Species comparison of liver proteomes reveals links to naked mole-rat longevity and human agingExternal link. BMC Biol. 2018 Aug 2;16(1):82. → CRA4

Schneble N, Muller J, Kliche S, Bauer R, Wetzker R, Bohmer FD, Wang ZQ, Muller JP (2017) The protein-tyrosine phosphatase DEP-1 promotes migration and phagocytic activity of microglial cells in part through negative regulation of fyn tyrosine kinaseExternal link. Glia 65:416-428. → CRA3 / CRA4

Pein H, Koeberle SC, Voelkel M, Schneider F, Rossi A, Thürmer M, Löser K, Sautebin L, Morrison H, Werz O, Koeberle A (2017) Vitamin A regulates Akt signaling through the phospholipid fatty acid compositionExternal link. FASEB J 31: 4566-4577 → CRA1 / CRA3

Weis S, Rubio I, Ludwig K, Weigel C, Jentho E (2017) Hormesis and Defense of Infectious Disease.External link Int J Mol Sci 18(6). → CRA3 / CRA4

Schäfer C, Göder A, Beyer M, Kiweler N, Mahendrarajah N, Rauch A, Nikolova T, Stojanovic N, Wieczorek M, Reich T, Tomicic MT, Linnebacher M, Sonnemann J, Dietrich S, Sellmer A, Mahboobi S, Heinzel T, Schneider G, and Krämer OH (2017) Class I histone deacetylases regulate p53/NF-kB crosstalk in cancer cellsExternal link. Cellular Signalling 29, 218-225. → CRA1

Schuhwerk H, Atteya R, Siniuk K, Wang ZQ (2017) PARPing for Balance in the Homeostasis of poly(ADP-ribosyl)ationExternal link. Semin Cell Dev Biol Mar;63:81-91. → CRA4

Zibrova D, Vandermoere F, Göransson O, Peggie M, Mariño KV, Knierim A, Spengler K, Weigert C, Viollet B, Morrice NA, Sakamoto K, Heller R. (2017) GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesisExternal link
Biochem J. 2017 Mar 7;474(6):983-1001. → CRA1

Frahm C, Srivastava A, Schmidt S, Mueller J, Groth M, Guenther M, Ji Y, Priebe S, Platzer M, Witte OW. (2017)  Transcriptional profiling reveals protective mechanisms in brains of long-lived miceExternal link. Neurobiol Aging. 2017 Apr;52:23-31. → CRA2

Seemann E, Sun M, Krueger S, Tröger J, Hou W, Haag N, Schüler S, Westermann M, Huebner CA, Romeike B, Kessels MM^§, Qualmann B^§. (2017) Deciphering caveolar functions by External linksyndapin III KO-mediated impairment of caveolar invaginationExternal link. Elife. 2017 Dec 5;6:e29854. doi: 10.7554/eLife.29854. → CRA2
^§shared corresponding authorship

Winkler R, Kosan C. (2017) Effects of HDACi on immunological functionsExternal link. Methods Mol Biol, 1510: 93-101 → CRA4

Kresinsky A, Schneble N, Schmidt C, Frister A, Bauer R,Wetzker R, Muller JP (2016) Phagocytosis of bone marrow derived macrophages is controlled by phosphoinositide 3-kinase gammaExternal link. Immunol Lett 180:9-16. → CRA3

Hemdan NY, Weigel C, Reimann CM, Gräler MH (2016) Modulating sphingosine 1-phosphate signaling with DOP or FTY720 alleviates vascular and immune defects in mouse sepsisExternal link. European Journal of Immunology 46, 2767-2777 → CRA4

Schink M, Leipold E, Schirmeyer J, Schönherr R, Hoshi T, Heinemann SH (2016) Reactive species modify NaV1.8 channels and affect action potentials in murine dorsal root ganglia neuronsExternal link. Pflugers Arch EJP Jan;468(1):99-110. → CRA3

Koeberle A, Löser K, Thürmer M (2016) Stearoyl-CoA desaturase-1 and adaptive stress signalingExternal link. BBA-MOL CELL BIOL L 1861: 1719-1726. → CRA1

Gottlieb-Abraham E, Gutman O, Pai GM, Rubio I, Henis YI. The residue at position 5 of the N-terminal region of Src and Fyn modulates their myristoylation, palmitoylation, and membrane interactionsExternal link. Mol Biol Cell. 2016;27(24):3926-36. → CRA4

Pai GM, Zielinski A, Koalick D, Ludwig K, Wang Z-Q, Borgmann K, Pospiech H, Rubio I. (2016) TSC loss distorts DNA replication programme and sensitises cells to genotoxic stressExternal link. Oncotarget 7(51):85365-80 → CRA4

Wales P, Schuberth CE, Aufschnaiter R, Fels J, García-Aguilar I, Janning A, Dlugos CP, Schäfer-Herte M, Klingner C, Wälte M, Kuhlmann J, Menis E, Hockaday Kang L, Maier KC, Hou W, Russo A, Higgs HN, Pavenstädt H, Vogl T, Roth J, Qualmann B, Kessels MM, Martin DE, Mulder B, Wedlich-Söldner R. (2016) Calcium-mediated actin reset (CaAR) mediates acute cell adaptationsExternal link. Elife. 2016 Dec 6;5:e19850. doi: 10.7554/eLife.19850. → CRA2

Kong YX, Li Y, Zhang WM, Yuan SX, Winkler R, Kröhnert U, Han JY, Tao Lin T, Zhou Y, Chen C, Miao P, Wang BB, Zhang JP, Yu ZY, Yu Zhang Y, Kosan C, Zeng H. (2016) Sepsis-induced thymic atrophy is associated with defects in early lymphopoiesisExternal link. Stem Cells, 34(12): 2902-2915 → CRA4

Winkler R, Kosan C. (2016) Effects of HDACi on immunological functionsExternal link. Methods Mol Biol, 1510: 93-101 → CRA4

Shabab M, Arnold MF, Penterman J, Wommack AJ, Bocker HT, Price PA, Griffitts JS, Nolan EM and Walker GC (2016) Disulfide cross-linking influences symbiotic activities of nodule peptide NCR247External link. Proc Natl Acad Sci U S A, 2016 Sep 6;113(36):10157-62

Khaminets A*, Heinrich T*, Mari M, Grumati P, Huebner AK, Akutsu M, Liebmann L, Stolz A, Nietzsche S, Koch N, Mauthe M, Katona I, Qualmann B, Weis J, Reggiori F, Kurth I^§, Hübner CA^§, Dikic I^§ (2015) Regulation of endoplasmic reticulum turnover by selective autophagyExternal link. Nature 522: 354-358.    *equal contribution and ^§shared senior authorship → CRA2

Ndongson-Dongmo B, Heller R, Hoyer D, Brodhun M, Bauer M, Winning J, Hirsch E, Wetzker R, Schlattmann P, Bauer R (2015) Phosphoinositide 3-kinase gamma controls inflammation-induced myocardial depression via sequential cAMP- and iNOS- signalingExternal link. Cardiovasc Res Nov 1;108(2):243-53. → CRA1 / CRA3

Reimann CM, Thuy AV, Weigel C, Gräler MH (2015) Sphingosine 1-phosphate (S1P) in cancer immunity and development.External link Transl Cancer Res doi: 10.3978/j.issn.2218-676X.2015.09.01 → CRA4

Wallert M, Schmölz L, Koeberle A, Krauth V, Glei M, Galli F, Werz O, Birringer M, Lorkowski S (2015) α-Tocopherol long-chain metabolite α-13'-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophagesExternal link. Mol Nutr Food Res 59: 1524-1534. → CRA1 / CRA3

Hou W, Izadi M, Nemitz S, Haag N, Kessels MM, Qualmann B (2015) The actin nucleator Cobl is controlled by calcium and calmodulinExternal link. PLoS Biol 13: e1002233. → CRA2

Stark H, Fichtner M, König R, Lorkowski S, Schuster S (2015). Causes of upregulation of glycolysis in lymphocytes upon stimulation. A comparison with other cell typesExternal link. Biochimie Nov;118:185-94. → CRA1 / CRA3

Schuster S, Boley D, Möller P, Stark H, Kaleta C (2015) Mathematical models for explaining the Warburg effect: A review focussed on ATP and biomass production.External link Biochem Soc Trans ec;43(6):1187-94. doi: 10.1016/j.biochi.2015.09.017. → CRA1

Schuster S, Boley D, Möller P, Kaleta C (2015a) A minimal model for explaining the higher ATP production in the Warburg effect. Proceed. GCB 2015, PeerJ PrePrints 3: e1609. → CRA1

Zobel T, Brinkmann K, Koch N, Schneider K, Seemann E, Fleige A, Qualmann B, Kessels MM, Bogdan S. (2015) Cooperative functions of the two F-BAR proteins Cip4 and Nostrin in the regulation of E-cadherin in epithelial morphogenesisExternal link. J Cell Sci. 2015 Feb 1;128(3):499-515. doi: 10.1242/jcs.155929. → CRA2

Frister A, Schmidt C, Schneble N, Brodhun M, Gonnert FA, Bauer M, Hirsch E, Müller JP, Wetzker R, Bauer R (2014) Phosphoinositide 3-kinase γ affects LPS-induced disturbance of blood-brain barrier via lipid kinase-independent control of cAMP in microglial cellsExternal link. Neuromol Med 16: 704-713 → CRA3

Rauch A, Hennig D, Schäfer C, Wirth M, Marx C, Heinzel T, Schneider G, Krämer OH (2014) Survivin and YM155: How faithful is the liaisonExternal link? Biochim Biophys Acta Rev Canc 1845: 202-220. → CRA1

Schneider K, Seemann E, Liebmann L, Ahuja R, Koch D, Westermann M, Hübner CA, Kessels MM^§, Qualmann B^§ (2014). ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and functionExternal link. J Cell Biol 205: 197-215. 
^§shared senior authorship → CRA2

Baple E*, Maroofian R*, Chioza BA*, Izadi M*, Cross HE, Al-Turki S, Barwick K, Wagner K, Coblentz R, Zainy T, Patton MA, Qualmann B, Hurles M, Kessels MM, Crosby AH. (2014) Mutations in KPTN cause macrocephaly, neurodevelopmental delay, and seizuresExternal link. Am J Hum Genet 94(1):87-94.       *shared authorships → CRA2

Weimer S, Priebs J, Kuhlow D, Groth M, Priebe S, Mansfeld J, Merry TL, Dubuis S, Laube B, Pfeiffer AF, Schulz TJ, Guthke R, Platzer M, Zamboni N, Zarse K, Ristow M (2014) D-Glucosamine supplementation extends lifespan of nematodes and of aging mice.External link Nature Communications 5: 3563. → CRA1

Segref A, Kevei E, Pokrzywa W, Schmeisser K, Mansfeld J, Livnat-Levanon N, Ensenauer R, Glickman MH, Ristow M, Hoppe T (2014) Pathogenesis of Human Mitochondrial Diseases Is Modulated by Reduced Activity of the ubiquitin/proteasome SystemExternal link. Cell Metabolism 19: 642-52. → CRA1

Madishetti S, Schneble N, König C, Hirsch E, Schulz S, Müller JP, Wetzker R (2014) PI3Ky integrates cAMP and Akt signalling of the μ-opioid receptorExternal link. Br J Pharmacol 171: 3328-3337. → CRA3

Schmidt C, Schneble N, Wetzker R (2014) The fifth dimension of innate immunityExternal link. J Cell Commun Signal 8: 363-367. → CRA3

Schumacher L*, Urbach A*, Lutzenburg M, Bidmon HJ, Witte OW (2014) Bihemispheric ischemic tolerance induced by a unilateral focal cortical lesionExternal link. Brain Res 1570: 54-60.  *shared first authorship → CRA3

Schmidt C, Schneble N, Muller JP, Bauer R, Perino A, Marone R, Rybalkin SD, Wymann MP, Hirsch E, Wetzker R (2013) Phosphoinositide 3-kinase gamma mediates microglial phagocytosis via lipid kinase-independent control of cAMPExternal link. Neuroscience 233:44-53. → CRA3

Ermolaeva MA, Segref A, Dakhovnik A, Ou HL, Schneider JI, Utermöhlen O, Hoppe T, Schumacher B. (2013) DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.External link Nature 501: 416-420. → CRA4

Leipold E, Liebmann L, Korenke GC, Heinrich T, Giesselmann S, Baets J, Ebbinghaus M, Goral RO, Stödberg T, Hennings JC, Bergmann M, Altmüller J, Thiele H, Wetzel A, Nürnberg P, Timmerman V, De Jonghe P, Blum R, Schaible HG, Weis J, Heinemann SH, Hübner CA, Kurth I (2013) A de novo gain-of-function mutation in SCN11A causes loss of pain perceptionExternal link. Nature Genet 45: 1399-1404. → CRA2 / CRA3

Schulz A, Baader SL, Niwa-Kawakita M, Jung MJ, Bauer R, Garcia C, Zoch A, Schacke S, Hagel C, Mautner VF, Hanemann CO, Dun XP, Parkinson DB, Weis J, Schröder JM, Gutmann DH, Giovannini M, Morrison H (2013) Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathyExternal link. Nat Neurosci 16: 426-433. → CRA2 / CRA3

Geißler KJ, Jung MJ, Riecken LB, Sperka T, Cui Y, Schacke S, Merkel U, Markwart R, Rubio I, Than ME, Than-Breithaupt C, Peuker S, Seifert R, Kaupp UB, Herrlich P, Morrison H (2013) Regulation of Son of sevenless by the membrane-actin linker protein ezrinExternal link. Proc Natl Acad Sci USA 110: 20587-20592. → CRA2 / CRA4

Nolze A, Schneider J, Keil R, Lederer M, Huttelmaier S, Kessels MM, Qualmann B, Hatzfeld M (2013) FMRP regulates actin filament organization via the armadillo protein p0071.External link RNA 19: 1483-1496. → CRA2

Schmeisser K*, Mansfeld J*, Kuhlow D, Weimer S, Priebe S, Heiland I, Birringer M, Groth M, Segref A, Kanfi Y, Price NL, Schmeisser S, Schuster S, Pfeiffer AFH, Guthke R, Platzer M, Hoppe T, Cohen HY, Zarse K, Sinclair DA, Ristow M (2013) Role of sirtuins in lifespan regulation is linked to methylation of nicotinamideExternal link. Nature Chemical Biology 9: 693-700 - *shared first authorship → CRA1

Ginter T, Bier C, Knauer SK, Sughra K, Hildebrand D, Münz T, Liebe T, Heller R, Henke A, Stauber RH, Reichardt W, Schmid JA, Kubatzky KF, Heinzel T, Krämer OH (2012) Histone deacetylase inhibitors block IFNγ-induced STAT1 phosphorylationExternal link. Cell Signal 24: 1453-1460. → CRA1

Wetzker R, Rubio I (2012) Hormetic signalling patternsExternal link. Dose Response 10: 83-90 → CRA3 / CRA4